

A woman will face various potential health challenges during the different stages of her life, as significant hormonal changes take place with age.1 This comprehensive guide sheds light on many of these challenges – including common reproductive, vaginal and urinary conditions – in order to support South African healthcare professionals as they explain these conditions and their potential treatments to their patients.
Hormonal Changes
Puberty is the process of the body maturing physically and sexually, and it is a time of major hormonal change.2 Puberty in girls usually begins between the ages of 8 and 13 years,2 causing physical changes like breast development, pubic hair growth, the start of menstruation (monthly periods) and growth in the size of the ovaries, uterus and labia.2
Puberty can also cause emotional turmoil as young teenagers struggle to come to terms with their changing bodies and worry about being different from their peers.2
The main hormones associated with puberty are oestrogen and progesterone.2,3
Description: Acne is a prevalent skin condition during puberty, affecting about 80% of teenagers and also young adults up to 30 years.4 Hormonal acne is often triggered by changes in androgen, oestrogen and progesterone hormone levels, which results in the skin producing more sebum (oil). This oil can then clog the skin’s pores, causing acne.4
Treatment:
Description: Irregular periods are common during the first few years of menstruation as the body adjusts to new hormonal levels.6
Treatment:
Description: Lack of iron can cause anaemia, with common symptoms such as:
Low iron levels can be caused by heavy periods or by not eating enough iron-rich foods.9 Pregnancy can also cause this condition.9
Treatment:
Did You Know? Over 50% of South African women are iron deficient.10
Description: Hormonal changes during puberty can affect mood and emotional well-being,2 and many young women experience conditions like PMS.11
Typical PMS symptoms include:11
Treatment:
There are many contraceptive options available for sexually active teenagers, including:
It is also important that teens and young adults have access to comprehensive sex education, to encourage healthy sexual behaviour and responsible contraceptive use, and to reduce the risk of sexually transmitted diseases (STDs).13,14
Did You Know? In South Africa, 42% of girls are sexually active by the age of 18.15
Exposure to comprehensive sex education in school is associated with less risky sexual behaviour and increased HIV testing in South African adolescent girls.14

Hormonal Changes
During the reproductive years, women experience regular menstrual cycles with associated hormonal fluctuations.16 The continuously rising and falling oestrogen and progesterone levels affect various aspects of health.17,18
Description: A UTI is an infection of the bladder (cystitis), urethra (urethritis) or kidneys (pyelonephritis).19 UTIs are very common, with 50% to 60% of adult women experiencing one in their lifetime.19 Sexual activity, spermicide use and lack of oestrogen after menopause are all risk factors for developing a UTI.19
Symptoms include painful, frequent urination and cloudy urine.19
Treatment:
Did You Know? South Africa has the highest prevalence of UTIs in sub-Saharan Africa, at 67.6%.20
Description: Thrush, also called candidiasis, is caused by an overgrowth of Candida albicans, a yeast which is naturally present in the vagina.21,22 This overgrowth can be caused by: 21
Symptoms include itching and a thick, white vaginal discharge.22
Treatment:
Description: Bacterial vaginosis is a common vaginal infection that occurs when the balance of flora in the vagina is disrupted.21
Symptoms include a grey or white vaginal discharge with a strong odour.23
Treatment:
Description: OAB is a condition characterised by an urgent and frequent need to urinate, often accompanied by incontinence (leaking of urine).24
It can be caused by increased sensation from small volumes of urine in the bladder, which may cause unwanted muscle contractions.24 It can also be a symptom of an underlying problem like:24
Treatment: